International Journal of Infectious Diseases
Volume 11, Issue 2 , Pages 161-165 , March 2007

Prophylactic effect of the anti-inflammatory drug diclofenac in experimental schistosomiasis mansoni

  • Nevine Guirguis Nessim

      Affiliations

    • Corresponding Author InformationCorresponding author. Current address: c/o Habib El Masry, Dar Consultants, POB 895 Cairo, 11511 Egypt. Tel.: +20 2 7363228; fax: +20 2 3461170.
    • ,
  • Soheir Mahmoud

Received 11 September 2005 ,Revised 20 December 2005 ,Accepted 5 January 2006.

  • Image Result

    Liver section of a representative of the infected control group of mice (8 weeks post infection), illustrating large cellular granuloma composed of a mixture of chronic inflammatory cells rich in eosi

    Liver section of a representative of the infected control group of mice (8 weeks post infection), illustrating large cellular granuloma composed of a mixture of chronic inflammatory cells rich in eosinophils. The intact cellular miracidium is seen inside the ovum. Adjacent hepatocytes show hydropic change and focal atypical hyperplasia (H&E×200) (mean diameter=140μm).

  • Image Result
    Liver section of a representative of the infected and orally treated low dose diclofenac mice showing a small hepatic fibrocellular granuloma (H&E×200) (mean diameter=137μm).;

    Liver section of a representative of the infected and orally treated low dose diclofenac mice showing a small hepatic fibrocellular granuloma (H&E×200) (mean diameter=137μm).

  • Image Result
    Liver section of a representative of the infected and orally treated high dose diclofenac mice showing a small hepatic fibrocellular granuloma (H&E×200) (mean diameter=123μm).;

    Liver section of a representative of the infected and orally treated high dose diclofenac mice showing a small hepatic fibrocellular granuloma (H&E×200) (mean diameter=123μm).

PII: S1201-9712(06)00065-8

doi: 10.1016/j.ijid.2006.01.004

International Journal of Infectious Diseases
Volume 11, Issue 2 , Pages 161-165 , March 2007

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