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Volume 13, Issue 6, Pages e459-e462 (November 2009)


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Mycobacterium celatum pulmonary infection mimicking pulmonary tuberculosis in a patient with ankylosing spondylitis

Che-Kim Tana, Chih-Cheng Laib, Chien-Hong Chouc, Po-Ren HsuehdCorresponding Author Informationemail address

Received 24 November 2008; accepted 17 December 2008. published online 09 March 2009.

Summary 

Mycobacterium celatum, a slow-growing acid-fast bacillus, is an uncommon cause of human infection, mainly occurring in patients with AIDS. Rarely, infections restricted to the lung and lymph nodes have been reported in immunocompetent hosts. We report herein a case of M. celatum pulmonary infection that mimicked pulmonary tuberculosis in a patient with ankylosing spondylitis. The literature was reviewed and clinical features of eight HIV-negative patients with M. celatum infection are discussed. The clinical presentation of M. celatum is indistinguishable from tuberculosis, especially in patients with a previous history of pulmonary tuberculosis. Proper treatment depends on a definitive identification of this pathogen, which requires 16S rDNA sequencing or mycolic acid high performance liquid chromatography analysis.

Corresponding Editor: Sheldon Brown, New York, USA

a Department of Intensive Care Medicine, Chi-Mei Medical Center, Yungkang, Tainan, Taiwan

b Departments of Internal Medicine, Yi-Min Hospital, Taipei, Taiwan

c Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan

d Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Corresponding Author InformationCorresponding author. Tel.: +886 2 23123456x65355.

PII: S1201-9712(09)00065-4

doi:10.1016/j.ijid.2008.12.014


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