International Journal of Infectious Diseases
Volume 14, Issue 2 , Pages e153-e157 , February 2010

Disseminated systemic Nocardia farcinica infection complicating alefacept and infliximab therapy in a patient with severe psoriasis

  • Jaffar A. Al-Tawfiq

      Affiliations

    • Internal Medicine Services Division, PO Box 76, Room A-428-2, Building 61, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran 31311, Saudi Arabia
    • Corresponding Author InformationCorresponding author. Tel.: +966 3 877 3524; fax: +966 3 877 3790.
    • ,
  • Adil A. Al-Khatti

      Affiliations

    • Oncology Services Division, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia

Received 8 December 2008 ,Revised 3 March 2009 ,Accepted 17 March 2009.

References 

  1. McNeil MM, Brown JM. The medically important actinomycetes: epidemiology and microbiology. Clin Microbiol Rev. 1994;7:357–417
  2. Burgert SJ. Nocardiosis: a clinical review. Infect Dis Clin Pract. 1999;8:27–32
  3. Sabuncuoğlu H, Cibali Açikgo ZZ, Caydere M, Ustün H, Semih Keskil I. Nocardia farcinica brain abscess: a case report and review of the literature. Neurocirugia (Astur). 2004;15:600–603
  4. Wallis RS, Broder M, Wong J, Beenhouwer D. Granulomatous infectious diseases associated with tumor necrosis factor antagonists. Clin Infect Dis. 2004;38:1261–1265
  5. Wallis RS, Broder M, Wong J, Beenhouwer D. Granulomatous infections due to tumor necrosis factor blockade: correction. Clin Infect Dis. 2004;39:1254–1255
  6. Fabre S, Gibert C, Lechiche C, Jorgensen C, Sany J. Primary cutaneous Nocardia otitidiscaviarum infection in a patient with rheumatoid arthritis treated with infliximab. J Rheumatol. 2005;32:2432–2433
  7. Singh SM, Rau NV, Cohen LB, Harris H. Cutaneous nocardiosis complicating management of Crohn's disease with infliximab and prednisone. CMAJ. 2004;171:1063–1064
  8. Menon KV, Stadheim L, Kamath PS, Wiesner RH, Gores GJ, Peine CJ, et al. A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis. Am J Gastroenterol. 2004;99:255–260
  9. Scheinfeld NJ. Alefacept: its safety profile, off-label uses, and potential as part of combination therapies for psoriasis. J Dermatolog Treat. 2007;18:197–208
  10. Prasertsuntarasai T, Bello EF. Mycobacterium avium complex olecranon bursitis in a patient treated with alefacept. Mayo Clin Proc. 2005;80:1532–1533
  11. Vamvouris T, Hadi S. A review of the treatment of psoriasis with infliximab. Rev Recent Clin Trials. 2006;1:201–205
  12. Toruner M, Loftus EV, Harmsen WS, Zinsmeister AR, Orenstein R, Sandborn WJ, et al. Risk factors for opportunistic infections in patients with inflammatory bowel disease. Gastroenterology. 2008;134:929–936
  13. Wendling D, Murad M, Mathieu S, Berger E, Rumbach L. Systemic nocardiosis in a case of rheumatoid arthritis treated with tumor necrosis factor blockers. J Rheumatol. 2008;35:539–542
  14. Doraiswamy VA. Nocardia infection with adalimumab in rheumatoid arthritis. J Rheumatol. 2008;35:542–543
  15. Torres OH, Domingo P, Pericas R, Boiron P, Montiel JA, Vázquez G. Infection caused by Nocardia farcinica: case report and review. Eur J Clin Microbiol Infect Dis. 2000;19:205–212
  16. Wauters G, Avesani V, Charlier J, Janssens M, Vaneechoutte M, Delmee M. Distribution of Nocardia species in clinical samples and their routine rapid identification in the laboratory. J Clin Microbiol. 2005;43:2624–2628
  17. Cercenado E, Marin M, Sanchez-Martinez M, Cuevas O, Martinez-Alarcon J, Bouza E. In vitro activities of tigecycline and eight other antimicrobials against different Nocardia species identified by molecular methods. Antimicrob Agents Chemother. 2007;51:1102–1104
  18. Wallace RJ, Steele LC, Sumter G, Smith JM. Antimicrobial susceptibility patterns of Nocardia asteroides. Antimicrob Agents Chemother. 1988;32:1776–1779
  19. Aydoslu B, Tuğrul HM. Nocardia spp isolated from immunocompromised patients in Trakya University Medical Faculty Hospital and their antibiotic susceptibilities. Mikrobiyol Bul. 2007;41:529–535
  20. Dodds EM, Echandi LV, Puente SI, Kaufman S. Subretinal abscess due to Nocardia farcinica resistant to trimethoprim–sulfamethoxazole in a patient with systemic lupus erythematosus. Ocul Immunol Inflamm. 2006;14:249–251
  21. Mamelak AN, Obana WG, Flaherty JF, Rosenblum ML. Nocardia brain abscess: treatment strategies and factors influencing outcome. Neurosurgery. 1994;35:622–631
  22. Steingrube VA, Brown BA, Gibson JL, Wilson RW, Brown J, Blacklock Z, et al. DNA amplification and restriction endonuclease analysis for differentiation of 12 different species and taxa of Nocardia, including recognition of four new taxa within the Nocardia asteroides complex. J Clin Microbiol. 1995;33:3096–3101
  23. Iannotti CA, Hall GS, Procop GW, Tuohy MJ, Staugaitis SM, Weil RJ. Solitary Nocardia farcinica brain abscess in an immunocompetent adult mimicking metastatic brain tumor: rapid diagnosis by pyrosequencing and successful treatment. Surg Neurol. 2008;[Epub ahead of print]

PII: S1201-9712(09)00153-2

doi: 10.1016/j.ijid.2009.03.017

International Journal of Infectious Diseases
Volume 14, Issue 2 , Pages e153-e157 , February 2010

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