International Journal of Infectious Diseases
Volume 14, Issue 2 , Pages e158-e160 , February 2010

Brucellosis presenting as myelofibrosis: First case report

  • Faris G. Bakri

      Affiliations

    • Department of Medicine, Division of Infectious Diseases, Jordan University Hospital, PO Box 13046, Amman 11942, Jordan
    • Corresponding Author InformationCorresponding author. Tel.: +962 6 5353666x2474; fax: +962 6 5353388.
    • ,
  • Nazzal M. Al-Bsoul

      Affiliations

    • Department of Medicine, Division of Hematology and Oncology, Jordan University Hospital, Amman, Jordan
    • ,
  • Ahmad Y. Magableh

      Affiliations

    • Department of Medicine, Division of Hematology and Oncology, Jordan University Hospital, Amman, Jordan
    • ,
  • Asem Shehabi

      Affiliations

    • Department of Pathology–Microbiology, Jordan University Hospital, Amman, Jordan
    • ,
  • Musleh Tarawneh

      Affiliations

    • Department of Pathology, Jordan University Hospital, Amman, Jordan
    • ,
  • Azmy M. Al-Hadidy

      Affiliations

    • Department of Radiology, Jordan University Hospital, Amman, Jordan
    • ,
  • Mohammed A. Abu-Fara

      Affiliations

    • Department of Medicine, Division of Infectious Diseases, Jordan University Hospital, PO Box 13046, Amman 11942, Jordan
    • ,
  • Abdallah S. Awidi

      Affiliations

    • Department of Medicine, Division of Hematology and Oncology, Jordan University Hospital, Amman, Jordan

Received 8 January 2009 ,Revised 8 March 2009 ,Accepted 15 March 2009.

References 

  1. Shehabi A, Shakir K, el-Khateeb M, Qubain H, Fararjeh N, Shamat AR. Diagnosis and treatment of 106 cases of human brucellosis. J Infect. 1990;20:5–10
  2. Colmenero JD, Reguera JM, Martos F, Sanchez-De-Mora D, Delgado M, Causse M, et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine (Baltimore). 1996;75:195–211
  3. Crosby E, Llosa L, Miro Quesada M, Carrillo C, Gotuzzo E. Hematologic changes in brucellosis. J Infect Dis. 1984;150:419–424
  4. Sari I, Altuntas F, Hacioglu S, Kocyigit I, Sevinc A, Sacar S, et al. A multicenter retrospective study defining the clinical and hematological manifestations of brucellosis and pancytopenia in a large series: hematological malignancies, the unusual cause of pancytopenia in patients with brucellosis. Am J Hematol. 2008;83:334–339
  5. Yildirmak Y, Palanduz A, Telhan L, Arapoglu M, Kayaalp N. Bone marrow hypoplasia during Brucella infection. J Pediatr Hematol Oncol. 2003;25:63–64
  6. Akdeniz H, Irmak H, Seckinli T, Buzgan T, Demiroz AP. Hematological manifestations in brucellosis cases in Turkey. Acta Med Okayama. 1998;52:63–65
  7. Karakukcu M, Patiroglu T, Ozdemir MA, Gunes T, Gumus H, Karakukcu C. Pancytopenia, a rare hematologic manifestation of brucellosis in children. J Pediatr Hematol Oncol. 2004;26:803–806
  8. Martin-Moreno S, Soto-Guzman O, Bernaldo-de-Quiros J, Reverte-Cejudo D, Bascones-Casas C. Pancytopenia due to hemophagocytosis in patients with brucellosis: a report of four cases. J Infect Dis. 1983;147:445–449
  9. Al-Eissa YA, Assuhaimi SA, al-Fawaz IM, Higgy KE, al-Nasser MN, al-Mobaireek KF. Pancytopenia in children with brucellosis: clinical manifestations and bone marrow findings. Acta Haematol. 1993;89:132–136
  10. Garcia P, Yrivarren JL, Argumans C, Crosby E, Carrillo C, Gotuzzo E. Evaluation of the bone marrow in patients with brucellosis. Clinico-pathological correlation. Enferm Infecc Microbiol Clin. 1990;8:19–24
  11. Namiduru M, Gungor K, Dikensoy O, Baydar I, Ekinci E, Karaoglan I, et al. Epidemiological, clinical and laboratory features of brucellosis: a prospective evaluation of 120 adult patients. Int J Clin Pract. 2003;57:20–24
  12. Al-Anazi KA, Al-Jasser AM. Brucella bacteremia in patients with acute leukemia: a case series. J Med Case Rep. 2007;1:144
  13. Barutca S, Sivri B. Brucellosis and hepatocellular carcinoma: just a coincidence?. Am J Gastroenterol. 1998;93:854–855
  14. Rocha Filho FD, Ferreira FV, Mendes Fde O, Ferreira FN, Karbage A, Alencar ML, et al. Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar. Rev Soc Bras Med Trop. 2000;33:363–366
  15. Hoffman R, Ravandi-Kashani F. Idiopathic myelofibrosis. In:  Hoffman R,  Benz EJ,  Shattil SJ,  Furie B,  Cohen HJ,  Silberstein LE,  McGlave P editor. Hematology: basic principles and practice. Philadelphia: Elsevier; 2005;p. 1255–1276
  16. Politano S, Maselli D, Zenali MJ, Nguyen A, Quintas-Cardama A. Bone marrow fibrosis and gelatinous atrophy associated with acute Epstein–Barr virus infection. Am J Hematol. 2008;83:606–607
  17. Viallard JF, Parrens M, Boiron JM, Texier J, Mercie P, Pellegrin JL. Reversible myelofibrosis induced by tuberculosis. Clin Infect Dis. 2002;34:1641–1643
  18. Rafiei A, Hajilooi M, Shakib RJ, Alavi SA. Transforming growth factor-beta1 polymorphisms in patients with brucellosis: an association between codon 10 and 25 polymorphisms and brucellosis. Clin Microbiol Infect. 2007;13:97–100
  19. Akbulut H, Celik I, Akbulut A. Cytokine levels in patients with brucellosis and their relations with the treatment. Indian J Med Microbiol. 2007;25:387–390
  20. Pullarkat V, Bass RD, Gong JZ, Feinstein DI, Brynes RK. Primary autoimmune myelofibrosis: definition of a distinct clinicopathologic syndrome. Am J Hematol. 2003;72:8–12
  21. Bakri FG, Wahbeh A, Mahafzah A, Tarawneh M. Brucella glomerulonephritis resulting in end-stage renal disease: a case report and a brief review of the literature. Int Urol Nephrol. 2008;40:529–533
  22. Massasso D, Gibson K. Brucellosis mimicking Henoch–Schonlein purpura. Med J Aust. 2007;186:602–603
  23. Pappas G, Kitsanou M, Christou L, Tsianos E. Immune thrombocytopenia attributed to brucellosis and other mechanisms of Brucella-induced thrombocytopenia. Am J Hematol. 2004;75:139–141

PII: S1201-9712(09)00154-4

doi: 10.1016/j.ijid.2009.03.018

International Journal of Infectious Diseases
Volume 14, Issue 2 , Pages e158-e160 , February 2010

Article Tools

* Image Usage & Resolution