International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e553-e559 , July 2010

A hypothetical explanatory model for meningococcal meningitis in the African meningitis belt

Received 24 November 2008 ,Revised 5 April 2009 ,Accepted 16 August 2009.

References 

  1. Greenwood B. Manson Lecture. Meningococcal meningitis in Africa. Trans R Soc Trop Med Hyg. 1999;93:341–353
  2. Lapeyssonnie L. La méningite cérébrospinale en Afrique. Bull World Health Organ. 1963;28(Suppl):1–114
  3. Molesworth AM, Thomson MC, Connor SJ, Cresswell MP, Morse AP, Shears P, et al. Where is the meningitis belt? Defining an area at risk of epidemic meningitis in Africa. Trans R Soc Trop Med Hyg. 2002;96:242–249
  4. Greenwood BM, Cleland PG, Haggie MH, Lewis LS, Macfarlane JT, Taqi A, et al. An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern. Trans R Soc Trop Med Hyg. 1979;73:563–566
  5. Mueller JE, Borrow R, Gessner BD. Meningococcal serogroup W135 in the African meningitis belt: epidemiology, immunity and vaccines. Expert Rev Vaccines. 2006;5:319–336
  6. Boisier P, Nicolas P, Djibo S, Taha MK, Jeanne I, Mainassara HB, et al. Meningococcal meningitis: unprecedented incidence of serogroup X-related cases in 2006 in Niger. Clin Infect Dis. 2007;44:657–663
  7. Trotter CL, Gay NJ, Edmunds WJ. Dynamic models of meningococcal carriage, disease, and the impact of serogroup C conjugate vaccination. Am J Epidemiol. 2005;162:89–100
  8. Thomson MC, Molesworth AM, Djingarey MH, Yameogo KR, Belanger F, Cuevas LE. Potential of environmental models to predict meningitis epidemics in Africa. Trop Med Int Health. 2006;11:781–788
  9. Yaka P, Sultan B, Broutin H, Janicot S, Philippon S, Fourquet N. Relationships between climate and year-to-year variability in meningitis outbreaks: a case study in Burkina Faso and Niger. Int J Health Geogr. 2008;7:34
  10. Sultan B, Labadi K, Guégan JF, Janicot S. Climate drives the meningitis epidemics onset in West Africa. PLoS Med. 2005;2:e6
  11. Molesworth AM, Cuevas LE, Connor SJ, Morse AP, Thomson MC. Environmental risk and meningitis epidemics in Africa. Emerg Infect Dis. 2003;9:1287–1293
  12. Moore PS. Meningococcal meningitis in sub-Saharan Africa: a model for the epidemic process. Clin Infect Dis. 1992;14:515–525
  13. Griffiss JM. Epidemic meningococcal disease: synthesis of a hypothetical immunoepidemiologic model. Rev Infect Dis. 1982;4:159–172
  14. EU-IBIS Network. Invasive Neisseria meningitidis in Europe 2006. London: Health Protection Agency; 2006. Available at: www.euibis.org (accessed February 9, 2009)
  15. Perrocheau A, Taha MK, Levy-Bruhl D. Epidemiology of invasive meningococcal disease in France in 2003. Euro Surveill. 2005;10:238–241
  16. Parent du Châtelet I, Taha MK, Lepoutre A, Lévy-Bruhl D. [Invasive meningococcal disease in France, 2006] (in French). Bulletin Épidémiologique Hebdomadaire. 2007;51–52:437–441
  17. Perrocheau A, Bonmarin I, Lévy-Bruhl D. Les infections invasives à méningocoques en France en 2002. Bulletin Épidémiologique Hebdomadaire. 2003;43:209–212
  18. Yaro S, Lourd M, Traore Y, Njanpop-Lafourcade BM, Sawadogo A, Sangare L, et al. Epidemiological and molecular characteristics of a highly lethal pneumococcal meningitis epidemic in Burkina Faso. Clin Infect Dis. 2006;43:693–700
  19. Boisier P, Djibo S, Sidikou F, Mindadou H, Kairo KK, Djibo A, et al. Epidemiological patterns of meningococcal meningitis in Niger in 2003 and 2004: under the threat of N. meningitidis serogroup W135. Trop Med Int Health. 2005;10:435–443
  20. Parent du Châtelet I, Traore Y, Gessner BD, Antignac A, Naccro B, Njanpop-Lafourcade BM, et al. Bacterial meningitis in Burkina Faso: surveillance using field-based polymerase chain reaction testing. Clin Infect Dis. 2005;40:17–25
  21. Traoré Y, Njanpop-Lafourcade BM, Adjogble KL, Lourd M, Yaro S, Nacro B, et al. The rise and fall of epidemic Neisseria meningitidis serogroup W135 meningitis in Burkina Faso, 2002–2005. Clin Infect Dis. 2006;43:817–822
  22. Leimkugel J, Adams FA, Gagneux S, Pfluger V, Flierl C, Awine E, et al. An outbreak of serotype 1 Streptococcus pneumoniae meningitis in northern Ghana with features that are characteristic of Neisseria meningitidis meningitis epidemics. J Infect Dis. 2005;192:192–199
  23. Mueller JE, Yaro S, Madec Y, Somda PK, Idohou RS, Njanpop Lafourcade BM, et al. The association of respiratory tract infection symptoms and air humidity with meningococcal carriage in Burkina Faso. Trop Med Int Health. 2008;13:1543–1552
  24. Greenwood BM, Greenwood AM, Bradley AK, Williams K, Hassan-King M, Shenton FC, et al. Factors influencing susceptibility to meningococcal disease during an epidemic in The Gambia, West Africa. J Infect. 1987;14:167–184
  25. Sié A, Pfluger V, Coulibaly B, Dangy JP, Kapaun A, Junghanss T, et al. ST-2859 serogroup A meningococcal meningitis outbreak in Nouna Health District, Burkina Faso: a prospective study. Trop Med Int Health. 2008;13:861–868
  26. Miller MA, Wenger J, Rosenstein N, Perkins B. Evaluation of meningococcal meningitis vaccination strategies for the meningitis belt in Africa. Pediatr Infect Dis J. 1999;18:1051–1059
  27. Pollard AJ, Frasch C. Development of natural immunity to Neisseria meningitidis. Vaccine. 2001;19:1327–1346
  28. Taha MK, Deghmane AE, Antignac A, Zarantonelli ML, Larribe M, Alonso JM. The duality of virulence and transmissibility in Neisseria meningitidis. Trends Microbiol. 2002;10:376–382
  29. Stephens D, Greenwood B, Brandtzaeg P. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet. 2007;369:2196–2210
  30. Trotter CL, Greenwood BM. Meningococcal carriage in the African meningitis belt. Lancet Infect Dis. 2007;7:797–803
  31. Leimkugel J, Hodgson A, Forgor AA, Pfluger V, Dangy JP, Smith T, et al. Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight-year longitudinal study in northern Ghana. PLoS Med. 2007;4:e101
  32. Mueller JE, Yaro S, Traore Y, Sangare L, Tarnagda Z, Njanpop-Lafourcade BM, et al. Neisseria meningitidis serogroups A and W-135: carriage and immunity in Burkina Faso, 2003. J Infect Dis. 2006;193:812–820
  33. Raghunathan PL, Jones JD, Tiendrebeogo SR, Sanou I, Sangare L, Kouanda S, et al. Predictors of immunity after a major serogroup W-135 meningococcal disease epidemic, Burkina Faso, 2002. J Infect Dis. 2006;193:607–616
  34. Amadou HA, Djibo S, Elhaj MA, Moussa A, Findlow H, Sidikou F, et al. Prospective survey on carriage of Neisseria meningitidis and protective immunity to meningococci in schoolchildren in Niamey (Niger): focus on serogroup W135. Microbes Infect. 2006;8:2098–2104
  35. MacLennan JM, Urwin R, Obaro S, Griffiths D, Greenwood B, Maiden MC. Carriage of serogroup W-135, ET-37 meningococci in The Gambia: implications for immunisation policy?. Lancet. 2000;356:1078
  36. Blakebrough IS, Greenwood BM, Whittle HC, Bradley AK, Gilles HM. The epidemiology of infections due to Neisseria meningitidis and Neisseria lactamica in a northern Nigerian community. J Infect Dis. 1982;146:626–637
  37. Burian V, Fofana Y, Sow O. [A study of Neisseria meningitidis isolated in the Republic of Mali in 1970] (in French). Bull World Health Organ. 1974;51:495–500
  38. Emele FE, Ahanotu CN, Anyiwo CE. Nasopharyngeal carriage of meningococcus and meningococcal meningitis in Sokoto. Nigeria. Acta Paediatr. 1999;88:265–269
  39. Evans-Jones LG, Whittle HC, Onyeowotu II, Egler LJ, Greenwood BM. Comparative study of group A and C meningococcal infection. Arch Dis Child. 1977;52:320–323
  40. Mueller JE, Sangaré L, Njanpop-Lafourcade BM, Tarnagda Z, Traoré Y, Yaro S, et al. Molecular characteristics and epidemiology of meningococcal carriage, Burkina Faso, 2003. Emerg Infect Dis. 2007;13:847–854
  41. Moore PS, Hierholzer J, DeWitt W, Djore D, Lippeveld T, Plikaytis B, et al. Respiratory viruses and Mycoplasma as cofactors for epidemic group A meningococcal meningitis. JAMA. 1990;264:1271–1275
  42. Young LS, LaForce FM, Head JJ, Feeley JC, Bennett JV. A simultaneous outbreak of meningococcal and influenza infections. N Engl J Med. 1972;287:5–9
  43. Alonso JM, Taha MK. [Respiratory virosis and invasive bacterial superinfections. The case for influenza and meningococcal diseases] (in French). Arch Pediatr. 2003;10:1013–1015
  44. Jacoby P, Watson K, Bowman J, Taylor A, Riley TV, Smith DW, et al. Modelling the co-occurrence of Streptococcus pneumoniae with other bacterial and viral pathogens in the upper respiratory tract. Vaccine. 2007;25:2458–2464
  45. Hament JM, Kimpen JL, Fleer A, Wolfs TF. Respiratory viral infection predisposing for bacterial disease: a concise review. FEMS Immunol Med Microbiol. 1999;26:189–195
  46. Alonso JM, Guiyoule A, Zarantonelli ML, Ramisse F, Pires R, Antignac A, et al. A model of meningococcal bacteremia after respiratory superinfection in influenza A virus-infected mice. FEMS Microbiol Lett. 2003;222:99–106
  47. Avadhanula V, Rodriguez CA, Devincenzo JP, Wang Y, Webby RJ, Ulett GC, et al. Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol. 2006;80:1629–1636
  48. Fainstein V, Musher DM, Cate TR. Bacterial adherence to pharyngeal cells during viral infection. J Infect Dis. 1980;141:172–176
  49. Santaniello-Newton A, Hunter PR. Management of an outbreak of meningococcal meningitis in a Sudanese refugee camp in Northern Uganda. Epidemiol Infect. 2000;124:75–81
  50. Nicolas P, Norheim G, Garnotel E, Djibo S, Caugant DA. Molecular epidemiology of Neisseria meningitidis isolated in the African Meningitis Belt between 1988 and 2003 shows dominance of sequence type 5 (ST-5) and ST-11 complexes. J Clin Microbiol. 2005;43:5129–5135
  51. Teyssou R, Muros E. Meningitis epidemics in Africa: a brief overview. Vaccine. 2007;25:A3–7
  52. Bertherat E, Yada A, Djingarey MH, Koumare B. [First major epidemic caused by Neisseria meningitidis serogroup W135 in Africa?] (in French). Med Trop. 2002;62:301–304
  53. Mayer LW, Reeves MW, Al-Hamdan N, Sacchi CT, Taha MK, Ajello GW, et al. Outbreak of W135 meningococcal disease in 2000: not emergence of a new W135 strain but clonal expansion within the electrophoretic type-13 complex. J Infect Dis. 2002;185:1596–1605

 This work was presented as a poster at the 7th Louis Pasteur Conference, Paris, France, November 11–13, 2008.

PII: S1201-9712(09)00348-8

doi: 10.1016/j.ijid.2009.08.013

International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e553-e559 , July 2010