International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e560-e566 , July 2010

Evolution of methicillin-resistant Staphylococcus aureus clones in Latin America

  • Eduardo Rodríguez-Noriega

      Affiliations

    • Hospital Civil de Guadalajara, Fray Antonio Alcalde, Instituto de Patología Infecciosa y Experimental, Centro Universitario Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico
    • Corresponding Author InformationCorresponding author. Tel.: +52 33 3614 5568; fax: +52 33 3685 0501.
    • ,
  • Carlos Seas

      Affiliations

    • Universidad Peruana Cayetano Heredia, Lima, Peru
    • ,
  • Manuel Guzmán-Blanco

      Affiliations

    • Centro Médico de Caracas, Caracas, Venezuela
    • ,
  • Carlos Mejía

      Affiliations

    • Hospital Roosevelt, Guatemala City, Guatemala
    • ,
  • Carlos Alvarez

      Affiliations

    • Hospital San Ignacio and Pontificia Universidad Javeriana, Bogotá, Colombia
    • ,
  • Luis Bavestrello

      Affiliations

    • Clinica Reñaca, Viña Del Mar, Chile
    • ,
  • Jeannete Zurita

      Affiliations

    • Hospital Vozandes, Quito, Ecuador
    • ,
  • Jaime Labarca

      Affiliations

    • Pontificia Universidad Católica de Chile, Santiago, Chile
    • ,
  • Carlos M. Luna

      Affiliations

    • Universidad de Buenos Aires, Buenos Aires, Argentina
    • ,
  • Mauro J.C. Salles

      Affiliations

    • Hospital Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil
    • ,
  • Eduardo Gotuzzo

      Affiliations

    • Universidad Peruana Cayetano Heredia, Lima, Peru
    • The authors or this review are all members of the Latin American Working Group on Gram Positive Resistance.

Received 18 December 2008 ,Revised 22 May 2009 ,Accepted 25 August 2009.

References 

  1. Ayliffe GA. The progressive intercontinental spread of methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 1997;24(Suppl 1):S74–S79
  2. Oliveira DC, Tomasz A, de Lencastre H. The evolution of pandemic clones of methicillin-resistant Staphylococcus aureus: identification of two ancestral genetic backgrounds and the associated mec elements. Microb Drug Resist. 2001;7:349–361
  3. Oliveira DC, Tomasz A, de Lencastre H. Secrets of success of a human pathogen: molecular evolution of pandemic clones of methicillin-resistant Staphylococcus aureus. Lancet Infect Dis. 2002;2:180–189
  4. Crisostomo MI, Westh H, Tomasz A, Chung M, Oliveira DC, de Lencastre H. The evolution of methicillin resistance in Staphylococcus aureus: similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones. Proc Natl Acad Sci U S A. 2001;98:9865–9870
  5. Chung M, Dickinson G, De Lencastre H, Tomasz A. International clones of methicillin-resistant Staphylococcus aureus in two hospitals in Miami. Florida. J Clin Microbiol. 2004;42:542–547
  6. Enright MC, Robinson DA, Randle G, Feil EJ, Grundmann H, Spratt BG. The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). Proc Natl Acad Sci U S A. 2002;99:7687–7692
  7. Feil EJ, Enright MC. Analyses of clonality and the evolution of bacterial pathogens. Curr Opin Microbiol. 2004;7:308–313
  8. Sader HS, Pignatari AC, Hollis RJ, Jones RN. Evaluation of interhospital spread of methicillin-resistant Staphylococcus aureus in Sao Paulo, Brazil, using pulsed-field gel electrophoresis of chromosomal DNA. Infect Control Hosp Epidemiol. 1994;15:320–323
  9. Maiden MC, Bygraves JA, Feil E, Morelli G, Russell JE, Urwin R, et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A. 1998;95:3140–3145
  10. Maiden MC. Multilocus sequence typing of bacteria. Annu Rev Microbiol. 2006;60:561–588
  11. Robinson DA, Enright MC. Evolutionary models of the emergence of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2003;47:3926–3934
  12. Ito T, Ma XX, Takeuchi F, Okuma K, Yuzawa H, Hiramatsu K. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob Agents Chemother. 2004;48:2637–2651
  13. Aires de Sousa M, Sanches IS, Ferro ML, Vaz MJ, Saraiva Z, Tendeiro T, et al. Intercontinental spread of a multidrug-resistant methicillin-resistant Staphylococcus aureus clone. J Clin Microbiol. 1998;36:2590–2596
  14. Aires de Sousa M, de Lencastre H, Santos Sanches I, Kikuchi K, Totsuka K, Tomasz A. Similarity of antibiotic resistance patterns and molecular typing properties of methicillin-resistant Staphylococcus aureus isolates widely spread in hospitals in New York City and in a hospital in Tokyo, Japan. Microb Drug Resist. 2000;6:253–258
  15. Simor AE, Ofner-Agostini M, Bryce E, McGeer A, Paton S, Mulvey MR. Laboratory characterization of methicillin-resistant Staphylococcus aureus in Canadian hospitals: results of 5 years of National Surveillance, 1995-1999. J Infect Dis. 2002;186:652–660
  16. Aires de Sousa M, Miragaia M, Sanches IS, Avila S, Adamson I, Casagrande ST, et al. Three-year assessment of methicillin-resistant Staphylococcus aureus clones in Latin America from 1996 to 1998. J Clin Microbiol. 2001;39:2197–2205
  17. Da Silva Coimbra MV, Teixeira LA, Ramos RL, Predari SC, Castello L, Famiglietti A, et al. Spread of the Brazilian epidemic clone of a multiresistant MRSA in two cities in Argentina. J Med Microbiol. 2000;49:187–192
  18. Senna JP, Pinto CA, Mateos S, Quintana A, Santos DS. Spread of a dominant methicillin-resistant Staphylococcus aureus (MRSA) clone between Uruguayan and South of Brazil Hospitals. J Hosp Infect. 2003;53:156–157
  19. Serri M, Balcells ME, García P, León E, Mella G, Lagos M, et al. Epidemiología molecular de Staphylococcus aureus meticilino-resistente. Estudio multicéntrico 2004–2005. In: Presentation at the XXII Congreso Chileno de Infectología. Puerto Varas, Chile, October. 2005;
  20. Balcells ME, García P, Salinas AM, Labarca J. Caracterización de clones de Staphylococcus aureus meticilino-resistente (SAMR) en un hospital clínico universitario chileno mediante epidemiología molecular. In: Presentation at the XXI Congreso Chileno de Infectología. Viña del Mar, Chile, October. 2004;
  21. Espinal P, Raciny M, Gaitan S, Muñoz A. First detection of Chilean clone in clinical isolates of methicillin-resistant Staphylococcus aureus in the Colombian–Caribbean region. Abstract No. R2348. Presented at the 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Barcelona, Spain, 19–22 April 2008.
  22. Buitrago G, Cortes JA, Castillo JS, Leal AL, Sanchez R, Alvarez CA. Methicillin-resistant Staphylococcus aureus. Community-acquired phenotype spread in hospitals in Bogotá, Colombia. Abstract No. P1438. Clin Microbiol Infect. 2008;14(s7):S411
  23. Beretta AL, Trabasso P, Stucchi RB, Moretti ML. Use of molecular epidemiology to monitor the nosocomial dissemination of methicillin-resistant Staphylococcus aureus in a university hospital from 1991 to 2001. Braz J Med Biol Res. 2004;37:1345–1351
  24. Teixeira LA, Resende CA, Ormonde LR, Rosenbaum R, Figueiredo AM, de Lencastre H, et al. Geographic spread of epidemic multiresistant Staphylococcus aureus clone in Brazil. J Clin Microbiol. 1995;33:2400–2404
  25. Teixeira LA, Lourenco MC, Figueiredo AM. Emergence of a methicillin-resistant Staphylococcus aureus clone related to the Brazilian epidemic clone III::B:A causing invasive disease among AIDS patients in a Brazilian hospital. Microb Drug Resist. 1996;2:393–399
  26. Corso A, Santos Sanches I, Aires de Sousa M, Rossi A, de Lencastre H. Spread of a methicillin-resistant and multiresistant epidemic clone of Staphylococcus aureus in Argentina. Microb Drug Resist. 1998;4:277–288
  27. Oliveira GA, Faria JB, Levy CE, Mamizuka EM. Characterization of the Brazilian endemic clone of methicillin-resistant Staphylococcus aureus (MRSA) from hospitals throughout Brazil. Braz J Infect Dis. 2001;5:163–170
  28. Amaral MM, Coelho LR, Flores RP, Souza RR, Silva-Carvalho MC, Teixeira LA, et al. The predominant variant of the Brazilian epidemic clonal complex of methicillin-resistant Staphylococcus aureus has an enhanced ability to produce biofilm and to adhere to and invade airway epithelial cells. J Infect Dis. 2005;192:801–810
  29. Ramos RL, Teixeira LA, Ormonde LR, Siqueira PL, Santos MS, Marangoni D, et al. Emergence of mupirocin resistance in multiresistant Staphylococcus aureus clinical isolates belonging to Brazilian epidemic clone III::B:A. J Med Microbiol. 1999;48:303–307
  30. dos Santos Soares MJ, da Silva-Carvalho MC, Ferreira-Carvalho BT, Figueiredo AM. Spread of methicillin-resistant Staphylococcus aureus belonging to the Brazilian epidemic clone in a general hospital and emergence of heterogenous resistance to glycopeptide antibiotics among these isolates. J Hosp Infect. 2000;44:301–308
  31. Gomes AR, Sanches IS, Aires de Sousa M, Castaneda E, de Lencastre H. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Colombian hospitals: dominance of a single unique multidrug-resistant clone. Microb Drug Resist. 2001;7:23–32
  32. Velazquez-Meza ME, Aires de Sousa M, Echaniz-Aviles G, Solorzano-Santos F, Miranda-Novales G, Silva-Sanchez J, et al. Surveillance of methicillin-resistant Staphylococcus aureus in a pediatric hospital in Mexico City during a 7-year period (1997 to 2003): clonal evolution and impact of infection control. J Clin Microbiol. 2004;42:3877–3880
  33. Sola C, Gribaudo G, Vindel A, Patrito L, Bocco JL. Identification of a novel methicillin-resistant Staphylococcus aureus epidemic clone in Cordoba, Argentina, involved in nosocomial infections. J Clin Microbiol. 2002;40:1427–1435
  34. Vivoni AM, Diep BA, de Gouveia Magalhaes AC, Santos KR, Riley LW, Sensabaugh GF, et al. Clonal composition of Staphylococcus aureus isolates at a Brazilian university hospital: identification of international circulating lineages. J Clin Microbiol. 2006;44:1686–1691
  35. Echaniz-Aviles G, Velazquez-Meza ME, Aires-de-Sousa M, Morfin-Otero R, Rodriguez-Noriega E, Carnalla-Barajas N, et al. Molecular characterisation of a dominant methicillin-resistant Staphylococcus aureus (MRSA) clone in a Mexican hospital (1999–2003). Clin Microbiol Infect. 2006;12:22–28
  36. Jeric PE, Matteo M, Soledad Ramirez M, Couto E, Tokumoto M, Centron D. Molecular characterization of methicillin-resistant Staphylococcus aureus isolates reveals the spreading of a new clone in Buenos Aires City. Medicina (B Aires). 2006;66:36–39
  37. Lamaro-Cardoso J, Castanheira M, de Oliveira RM, e Silva SA, Pignatari AC, Mendes RE, et al. Carriage of methicillin-resistant Staphylococcus aureus in children in Brazil. Diagn Microbiol Infect Dis. 2007;57:467–470
  38. Akpaka PE, Kissoon S, Rutherford C, Swanston WH, Jayaratne P. Molecular epidemiology of methicillin-resistant Staphylococcus aureus isolates from regional hospitals in Trinidad and Tobago. Int J Infect Dis. 2007;11:544–548
  39. Sola C, Cortes P, Saka HA, Vindel A, Bocco JL. Evolution and molecular characterization of methicillin-resistant Staphylococcus aureus epidemic and sporadic clones in Córdoba. Argentina. J Clin Microbiol. 2006;44:192–200
  40. Rozenbaum R, Silva-Carvalho MC, Souza RR, Melo MC, Gobbi CN, Coelho LR, et al. Molecular characterization of methicillin-resistant Staphylococcus aureus disseminated in a home care system. Infect Control Hosp Epidemiol. 2006;27:1041–1050
  41. Cruz C, Moreno J, Renzoni A, Hidalgo M, Reyes J, Schrenzel J, et al. Tracking methicillin-resistant Staphylococcus aureus clones in Colombian hospitals over 7 years (1996–2003): emergence of a new dominant clone. Int J Antimicrob Agents. 2005;26:457–462
  42. de Miranda OP, Silva-Carvalho MC, Ribeiro A, Portela F, Cordeiro RP, Caetano N, et al. Emergence in Brazil of methicillin-resistant Staphylococcus aureus isolates carrying SCCmecIV that are related genetically to the USA800 clone. Clin Microbiol Infect. 2007;13:1165–1172
  43. Ribeiro A, Dias C, Silva-Carvalho MC, Berquo L, Ferreira FA, Santos RN, et al. First report of infection with community-acquired methicillin-resistant Staphylococcus aureus in South America. J Clin Microbiol. 2005;43:1985–1988
  44. Ma XX, Galiana A, Pedreira W, Mowszowicz M, Christophersen I, Machiavello S, et al. Community-acquired methicillin-resistant Staphylococcus aureus, Uruguay. Emerg Infect Dis. 2005;11:973–976
  45. Gardella N, Picasso R, Predari SC, Lasala M, Foccoli M, Benchetrit G, et al. Methicillin-resistant Staphylococcus aureus strains in Buenos Aires teaching hospitals: replacement of the multidrug resistant South American clone by another susceptible to rifampin, minocycline and trimethoprim–sulfamethoxazole. Rev Argent Microbiol. 2005;37:156–160
  46. Perez LR, D’Azevedo PA. Clonal types and antimicrobial resistance profiles of methicillin-resistant Staphylococcus aureus isolates from hospitals in south Brazil. Rev Inst Med Trop Sao Paulo. 2008;50:135–137
  47. Melo MC, Silva-Carvalho MC, Ferreira RL, Coelho LR, Souza RR, Gobbi CN, et al. Detection and molecular characterization of a gentamicin-susceptible, methicillin-resistant Staphylococcus aureus (MRSA) clone in Rio de Janeiro that resembles the New York/Japanese clone. J Hosp Infect. 2004;58:276–285
  48. Ribeiro A, Coronado AZ, Silva-Carvalho MC, Ferreira-Carvalho BT, Dias C, Rozenbaum R, et al. Detection and characterization of international community-acquired infections by methicillin-resistant Staphylococcus aureus clones in Rio de Janeiro and Porto Alegre cities causing both community- and hospital-associated diseases. Diagn Microbiol Infect Dis. 2007;59:339–345
  49. Sola C, Saka HA, Vindel A, Bocco JL. Emergence and dissemination of a community-associated methicillin-resistant Panton–Valentine leucocidin-positive Staphylococcus aureus clone sharing the sequence type 5 lineage with the most prevalent nosocomial clone in the same region of Argentina. J Clin Microbiol. 2008;46:1826–1831
  50. Mayor L, Ortellado J, Menacho C, Lird G, Courtier C, Gardon C, et al. Molecular characterization of methicillin-resistant Staphylococcus aureus isolates collected in Asuncion, Paraguay. J Clin Microbiol. 2007;45:2298–2300
  51. Trindade PA, Pacheco RL, Costa SF, Rossi F, Barone AA, Mamizuka EM, et al. Prevalence of SCCmec type IV in nosocomial bloodstream isolates of methicillin-resistant Staphylococcus aureus. J Clin Microbiol. 2005;43:3435–3437
  52. Goering RV, Shawar RM, Scangarella NE, O’Hara FP, Amrine-Madsen H, West JM, et al. Molecular epidemiology of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from global clinical trials. J Clin Microbiol. 2008;46:2842–2847
  53. Shopsin B, Mathema B, Zhao X, Martinez J, Kornblum J, Kreiswirth BN. Resistance rather than virulence selects for the clonal spread of methicillin-resistant Staphylococcus aureus: implications for MRSA transmission. Microb Drug Resist. 2000;6:239–244
  54. Gordon RJ, Lowy FD. Pathogenesis of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis. 2008;46(Suppl 5):S350–S359
  55. Boucher HW, Corey GR. Epidemiology of methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2008;46(Suppl 5):S344–S349
  56. Casellas JM. Comité Resistencia Antibacterianos API. Resultados encuesta número 7. Revista Panamericana de Infectología. 2006;8:48–51
  57. Robicsek A, Beaumont JL, Paule SM, Hacek DM, Thomson RB, Kaul KL, et al. Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med. 2008;148:409–418
  58. Dellit TH, Owens RC, McGowan JE, Gerding DN, Weinstein RA, Burke JP, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2007;44:159–177

PII: S1201-9712(09)00354-3

doi: 10.1016/j.ijid.2009.08.018

International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e560-e566 , July 2010

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