International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e602-e607 , July 2010

Human immunodeficiency virus–hepatitis C virus co-infection in pregnant women and perinatal transmission to infants in Thailand

  • Nicole Ngo-Giang-Huong

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
    • Harvard School of Public Health, Boston, Massachusetts, USA
    • Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
    • Corresponding Author InformationCorresponding author. Tel.: +66 53 894 431; fax: +66 53 894 220.
  • ,
  • Gonzague Jourdain

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
    • Harvard School of Public Health, Boston, Massachusetts, USA
    • Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
  • ,
  • Wasna Sirirungsi

      Affiliations

    • Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
  • ,
  • Luc Decker

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
  • ,
  • Woottichai Khamduang

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
  • ,
  • Sophie Le Cœur

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
    • Institut National d’Etudes Demographiques, Université Paris Descartes, Paris, France
  • ,
  • Surat Sirinontakan

      Affiliations

    • Health Promotion Hospital Regional Center I, Bangkok, Thailand
  • ,
  • Rosalin Somsamai

      Affiliations

    • Lamphun Hospital, Lamphun, Thailand
  • ,
  • Karin Pagdi

      Affiliations

    • Lamphun Hospital, Lamphun, Thailand
  • ,
  • Jittapol Hemvuttiphan

      Affiliations

    • Phayao Hospital, Phayao, Thailand
  • ,
  • Kenneth McIntosh

      Affiliations

    • Department of Pediatrics, Harvard Medical School, Children's Hospital Boston, Boston, USA
  • ,
  • Francis Barin

      Affiliations

    • Laboratoire de Virologie and Centre National de Référence pour le VIH, Université F. Rabelais, Tours, France
  • ,
  • Marc Lallemant

      Affiliations

    • Institut de Recherche pour le Développement (IRD), U174 – Program for HIV Prevention and Treatment (PHPT), Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
    • Harvard School of Public Health, Boston, Massachusetts, USA
    • Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand

Received 1 May 2009 ,Revised 31 August 2009 ,Accepted 7 September 2009.

  • Image Result

    HCV infection status of HIV-infected and HIV-uninfected pregnant women and HCV infection status for children born to HIV–HCV-co-infected women. Among the 30 HIV–HCV-co-infected women with HCV viremia,

    HCV infection status of HIV-infected and HIV-uninfected pregnant women and HCV infection status for children born to HIV–HCV-co-infected women. Among the 30 HIV–HCV-co-infected women with HCV viremia, one woman delivered twins. Two children could not be assessed for HCV infection since no blood samples were available.

  • Image Result
    Distribution of plasma HCV RNA concentrations (panel a) and CD4 lymphocyte counts (panel b) among HIV–HCV-co-infected mothers who transmitted (transmitters) or did not transmit (non-transmitters) HCV

    Distribution of plasma HCV RNA concentrations (panel a) and CD4 lymphocyte counts (panel b) among HIV–HCV-co-infected mothers who transmitted (transmitters) or did not transmit (non-transmitters) HCV to their infants. Middle horizontal lines indicate medians.

 This work was presented in part at the 5th Dominique Dormont International Conference, Paris, France, March 26–28, 2009.

PII: S1201-9712(09)00360-9

doi: 10.1016/j.ijid.2009.09.002

International Journal of Infectious Diseases
Volume 14, Issue 7 , Pages e602-e607 , July 2010