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Coronavirus (COVID-19) Collection
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- Short CommunicationOpen Access
Transient increase in plasma HIV RNA after COVID-19 vaccination with mRNA-1272
International Journal of Infectious DiseasesVol. 113p125–126Published online: October 16, 2021- Giorgio Bozzi
- Andrea Lombardi
- Serena Ludovisi
- Antonio Muscatello
- Lara Manganaro
- Dario Cattaneo
- and others
Cited in Scopus: 6The latent viral reservoir is the main obstacle preventing HIV eradication, as the virus persists, integrated in long-lived quiescent cells. Immune stimulatory by their nature, vaccines have been evaluated as possible agents for ‘shock and kill’ strategies, which rely on using latency-reversing agents to activate HIV transcription and virion production in order to purge the reservoir.
