Coronavirus (COVID-19) Collection
Risk Factors Associated with Severe/Critical COVID-19 in People Living with HIV-1Risk factors have been described as associated with severe forms of COVID-19 (Zhang et al., 2020). Persons living with HIV-1 (PLWH1) often carry such comorbidities. As shown by Bhaskaran et al (2021), PLWH1 are at a greater risk of developing a severe form of COVID-19. Our objective was to determine the characteristics associated with the development of a severe or critical form of COVID-19 in a cohort of PLWH1 who were followed up at the Bichat-Claude Bernard University Hospital in Paris, France.
Transient increase in plasma HIV RNA after COVID-19 vaccination with mRNA-1272The latent viral reservoir is the main obstacle preventing HIV eradication, as the virus persists, integrated in long-lived quiescent cells. Immune stimulatory by their nature, vaccines have been evaluated as possible agents for ‘shock and kill’ strategies, which rely on using latency-reversing agents to activate HIV transcription and virion production in order to purge the reservoir.
HIV care in times of the COVID-19 crisis — Where are we now in Central and Eastern Europe?The SARS-CoV-2 pandemic has hit the European region disproportionately. Many HIV clinics share staff and logistics with infectious disease facilities, which are now on the frontline in tackling COVID-19. Therefore, this study investigated the impact of the current pandemic situation on HIV care and continuity of antiretroviral treatment (ART) supplies in CEE countries.
One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4+ T-cell countSince December 2019, an outbreak of coronavirus disease, officially named by the World Health Organization as COVID-19, appeared in Wuhan, Hubei Province, China. Patients present with severe viral pneumonia and respiratory illness. Lymphopenia has been considered as a poor prognostic factor for severe acute respiratory syndrome (SARS) (Leung et al., 2004) as well as COVID-19 (Qin et al., 2020). This study reports the clinical findings from a patient confirmed with COVID-19 who was also co-infected by human immunodeficiency virus (HIV).