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International Journal of Infectious Diseases
International Society for Infectious Diseases
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  • Rapid Communication
    Open Access

    The strength of association between pre-and post-booster BNT162b2 anti-SARS-CoV-2 antibodies levels depends on the immunoassay

    International Journal of Infectious Diseases
    Vol. 111p65–67Published online: August 26, 2021
    • Gian Luca Salvagno
    • Brandon M. Henry
    • Giuseppe Lippi
    Cited in Scopus: 4
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      Reliable evidence suggests that anticipating a humoral response to coronavirus disease 2019 (COVID-19) vaccines is essential for predicting their clinical effectiveness. Bergwerk et al. conducted a study in the largest medical center in Israel, where healthcare workers who received the Pfizer mRNA COVID-19 BNT162b2 vaccine were followed up with molecular or antigen testing, serologic assays, and genomic sequencing (Bergwerk et al., 2021). Notably, the levels of anti-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) neutralizing antibody and anti-SARS-CoV-2 IgG were found to be nearly 64% and 49% lower in infected subjects than in matched uninfected controls.
      The strength of association between pre-and post-booster BNT162b2 anti-SARS-CoV-2 antibodies levels depends on the immunoassay
    • Short Communication
      Open Access

      Main differences between the first and second waves of COVID-19 in Madrid, Spain

      International Journal of Infectious Diseases
      Vol. 105p374–376Published online: March 5, 2021
      • Vicente Soriano
      • Pilar Ganado-Pinilla
      • Miguel Sanchez-Santos
      • Felix Gómez-Gallego
      • Pablo Barreiro
      • Carmen de Mendoza
      • and others
      Cited in Scopus: 59
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        The emergence and rapid global spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), from Wuhan, China at the end of 2019 represented an unprecedented phenomenon in medicine. COVID-19 continues to challenge health services and disrupt social and economic activities globally. In Spain, the first wave commenced in mid-March 2020 and lasted for 3 months. It finally abated due to strict lockdown and home confinement. Following relaxation of measures during the summer, a second wave commenced in mid-September 2020 and extended until Christmas 2020.
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