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International Journal of Infectious Diseases
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  • Editorial
    Open Access

    Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapies

    International Journal of Infectious Diseases
    Vol. 96p431–439Published online: May 17, 2020
    • Alimuddin Zumla
    • Fu-Sheng Wang
    • Giuseppe Ippolito
    • Nicola Petrosillo
    • Chiara Agrati
    • Esam I. Azhar
    • Chao Chang
    • Sherif A. El-Kafrawy
    • Mohamed Osman
    • Laurence Zitvogel
    • Peter R. Galle
    • Franco Locatelli
    • Ellen Gorman
    • Carlos Cordon-Cardo
    • Cecilia O’Kane
    • Danny McAuley
    • Markus Maeurer
    Cited in Scopus: 38
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      As of May 17th 2020, the novel coronavirus disease 2019 (COVID-19) pandemic has caused 307,395 deaths worldwide, out of 3,917,366 cases reported to the World Health Organization. No specific treatments for reducing mortality or morbidity are yet available. Deaths from COVID-19 will continue to rise globally until effective and appropriate treatments and/or vaccines are found. In search of effective treatments, the global medical, scientific, pharma and funding communities have rapidly initiated over 500 COVID-19 clinical trials on a range of antiviral drug regimens and repurposed drugs in various combinations.
      Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapies
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