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International Journal of Infectious Diseases
International Society for Infectious Diseases
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  • Research Article
    Open Access

    Differential clinical characteristics and performance of home antigen tests between parents and children after household transmission of SARS-CoV-2 during the Omicron variant pandemic

    International Journal of Infectious Diseases
    Vol. 128p301–306Published online: January 12, 2023
    • Szu-Han Chen
    • Jhong-Lin Wu
    • Yun-Chung Liu
    • Ting-Yu Yen
    • Chun-Yi Lu
    • Luan-Yin Chang
    • and others
    Cited in Scopus: 0
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      The SARS-CoV-2 Omicron variant (B.1.1.529) BA.2 pandemic struck in 2022. Children seemed to have a lower rate of infection than adults at the beginning of the COVID-19 pandemic, but the clinical scenario changed, especially after the Omicron variant outbreak [1]. The transmission of SARS-CoV-2 may vary according to different viral variants, settings, and individuals, and understanding the transmission rate and factors associated with transmission may help further control COVID-19. To this end, the difference in clinical symptoms and overall household transmission rate between children and adults needs further investigation.
      Differential clinical characteristics and performance of home antigen tests between parents and children after household transmission of SARS-CoV-2 during the Omicron variant pandemic
    • Research Article
      Open Access

      Multicenter, Single-Blind, Randomized Controlled Study of the Efficacy and Safety of Favipiravir and Nafamostat Mesilate in Patients with COVID-19 Pneumonia

      International Journal of Infectious Diseases
      In Press Journal Pre-Proof
      Published online: January 3, 2023
      • Mahoko Ikeda
      • Shu Okugawa
      • Kosuke Kashiwabara
      • Takashi Moritoyo
      • Yoshiaki Kanno
      • Daisuke Jubishi
      • and others
      Cited in Scopus: 0
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        Introduction
        Multicenter, Single-Blind, Randomized Controlled Study of the Efficacy and Safety of Favipiravir and Nafamostat Mesilate in Patients with COVID-19 Pneumonia
      • Research Article
        Open Access

        COVID-19 and kidney transplantation: the impact of remdesivir on renal function and outcome - a retrospective cohort study

        International Journal of Infectious Diseases
        Vol. 118p247–253Published online: March 14, 2022
        • Florin Elec
        • Jesper Magnusson
        • Alina Elec
        • Adriana Muntean
        • Oana Antal
        • Tudor Moisoiu
        • and others
        Cited in Scopus: 2
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          Lifelong immunosuppression and the burden of comorbidities put organ transplant recipients at risk for unfavorable outcome after SARS-CoV-2 infection (Qin et al., 2021, Jager et al., 2020). The initial lack of knowledge concerning this new and puzzling disease as well as the absence of targeted and effective antiviral interventions during the early phases of the pandemic resulted in a mortality of kidney transplant (KTx) recipients exceeding 25% (Oltean et al., 2020). However, rapidly accumulating information, evolving guidelines, and several experimental treatments seem to have improved the outcomes following COVID-19 both in transplanted patients and the general population (Heldman et al., 2021, Elec et al., 2021, Villanego et al., 2021).
          COVID-19 and kidney transplantation: the impact of remdesivir on renal function and outcome - a retrospective cohort study
        • Research Article
          Open Access

          T-cell receptor repertoires as potential diagnostic markers for patients with COVID-19

          International Journal of Infectious Diseases
          Vol. 113p308–317Published online: October 21, 2021
          • Xianliang Hou
          • Guangyu Wang
          • Wentao Fan
          • Xiaoyan Chen
          • Chune Mo
          • Yongsi Wang
          • and others
          Cited in Scopus: 4
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            Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly worldwide (Lai et al., 2020). As of June 20, 2021, SARS-CoV-2 had affected more than 179 060 045 people globally, causing over 3.87 million deaths. In the USA, as many as 34 401 766 individuals had tested positive for COVID-19, and the death toll had reached 617 091 people (Baidu, 2021). The symptoms of COVID-19 include a dry cough, fever, diarrhea, fatigue, pneumonia, and conjunctivitis.
            T-cell receptor repertoires as potential diagnostic markers for patients with COVID-19
          • Research Article
            Open Access

            SARS-CoV-2 rapid antigen testing in the healthcare sector: A clinical prediction model for identifying false negative results

            International Journal of Infectious Diseases
            Vol. 112p117–123Published online: September 10, 2021
            • Johannes Leiner
            • Vincent Pellissier
            • Anne Nitsche
            • Sebastian König
            • Sven Hohenstein
            • Irit Nachtigall
            • and others
            Cited in Scopus: 0
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              Since its onset (Zhu et al., 2020), the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged to a major burden for the population in general but especially brought great challenges for the healthcare sector (Miller et al., 2020). Recent statistics presented by the German federal government agency Robert-Koch-Institute (RKI) show that cough, fever, nasal congestion, sore throat and loss of smell or taste are the most common symptoms caused by COVID-19 (RKI, 2021a).
              SARS-CoV-2 rapid antigen testing in the healthcare sector: A clinical prediction model for identifying false negative results
            • Research Article
              Open Access

              Inverse association between hypertension treatment and COVID-19 prevalence in Japan

              International Journal of Infectious Diseases
              Vol. 108p517–521Published online: June 2, 2021
              • Masako Kinoshita
              • Kazuaki Sato
              • Balachandar Vellingiri
              • Shawn J. Green
              • Masami Tanaka
              Cited in Scopus: 2
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                SARS-CoV-2 is the causative virus for COVID-19. Cell entry of SARS-CoV-2 depends on angiotensin-converting enzyme II (ACE2), which is a membrane-associated zinc peptidase, and transmembrane serine protease 2, which is a cellular serine protease (Zhou et al., 2020b; Hoffmann et al., 2020; Hirano and Murakami, 2020). ACE2 is homologous with, but acts antagonistically to, angiotensin-converting enzyme (ACE) and has the critical function of protecting the lungs from severe acute injury (Imai et al., 2005).
                Inverse association between hypertension treatment and COVID-19 prevalence in Japan
              • Research Article
                Open Access

                The spatiotemporal trend of renal involvement in COVID-19: A pooled analysis of 17 134 patients

                International Journal of Infectious Diseases
                Vol. 106p281–288Published online: April 3, 2021
                • Yi-Fu Feng
                • Kun-Peng Wang
                • Jing-Gang Mo
                • Ying-He Xu
                • Lie-Zhi Wang
                • Chong Jin
                • and others
                Cited in Scopus: 0
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                  Coronavirus disease 2019 (COVID-19) is a novel respiratory infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has reopened the issue of the role and importance of coronaviruses in human pathology (World Health Organization, 2020a). In fact, only seven coronaviruses are known to be zoonotic, with the ability to jump from animals to humans. Four of them cause mild illnesses, such as the common cold, while the other three types have had more catastrophic consequences: severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and now SARS-CoV-2 (Čivljak et al., 2020).
                  The spatiotemporal trend of renal involvement in COVID-19: A pooled analysis of 17 134 patients
                • Research Article
                  Open Access

                  Factors associated with a prolonged negative conversion of viral RNA in patients with COVID-19

                  International Journal of Infectious Diseases
                  Vol. 105p463–469Published online: February 26, 2021
                  • Cyrine Bennasrallah
                  • Imen Zemni
                  • Wafa Dhouib
                  • Haythem Sriha
                  • Nourhene Mezhoud
                  • Samar Bouslama
                  • and others
                  Cited in Scopus: 9
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                    Cases of pneumonia of unknown etiology were first reported from Wuhan, Hubei Province, China in December 2019 (Shi et al., 2020). In February 2020, the World Health Organization (WHO) named this emerging disease coronavirus disease 2019 (COVID-19) and the agent responsible was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Lai et al., 2020).
                    Factors associated with a prolonged negative conversion of viral RNA in patients with COVID-19
                  • Research Article
                    Open Access

                    Efficacy evaluation of intravenous immunoglobulin in non-severe patients with COVID-19: A retrospective cohort study based on propensity score matching

                    International Journal of Infectious Diseases
                    Vol. 105p525–531Published online: January 9, 2021
                    • Chenlu Huang
                    • Ling Fei
                    • Weixia Li
                    • Wei Xu
                    • Xudong Xie
                    • Qiang Li
                    • and others
                    Cited in Scopus: 9
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                      In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused an outbreak of coronavirus disease 2019 (COVID-19) (Wu et al., 2020). Person-to-person transmission of SARS-CoV-2 has been confirmed, and individuals with asymptomatic infections have been identified as potential infection sources (Chan et al., 2020; Rothe et al., 2020). To date, SARS-CoV-2 has spread to almost all countries worldwide, and the number of confirmed cases and deaths has been growing rapidly due to the high rate of infectivity (R0).
                      Efficacy evaluation of intravenous immunoglobulin in non-severe patients with COVID-19: A retrospective cohort study based on propensity score matching
                    • Research Article
                      Open Access

                      The impact of universal face masking and enhanced hand hygiene for COVID-19 disease prevention on the incidence of hospital-acquired infections in a Taiwanese hospital

                      International Journal of Infectious Diseases
                      Vol. 104p15–18Published online: December 28, 2020
                      • Shih-Hao Lo
                      • Chun-Yu Lin
                      • Ching-Tzu Hung
                      • Jyun-Ji He
                      • Po-Liang Lu
                      Cited in Scopus: 17
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                        Since December 2019, coronavirus disease 2019 (COVID-19) has spread rapidly from Wuhan, Hubei Province, People’s Republic of China, around the world (Chen et al., 2020). COVID-19 was first detected in Taiwan on 21 January 2020 (Cheng et al., 2020). During the stressful and distressing time of the severe acute respiratory syndrome (SARS) epidemic in 2003, the Taiwanese government implemented wide-ranging preventive actions, including: public health education, medical resources allocation, enhanced case identification, high-risk group quarantine, and restriction of patient visitors in healthcare facilities or hospitals (Hsu et al., 2020; Wang et al., 2020).
                        The impact of universal face masking and enhanced hand hygiene for COVID-19 disease prevention on the incidence of hospital-acquired infections in a Taiwanese hospital
                      • Research Article
                        Open Access

                        New loss of smell and taste: Uncommon symptoms in COVID-19 patients on Nord Franche-Comte cluster, France

                        International Journal of Infectious Diseases
                        Vol. 100p117–122Published online: August 6, 2020
                        • Timothée Klopfenstein
                        • Hajer Zahra
                        • N’dri Juliette Kadiane-Oussou
                        • Quentin Lepiller
                        • Pierre-Yves Royer
                        • Lynda Toko
                        • and others
                        Cited in Scopus: 49
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                          We included 70 patients infected with SARS-CoV-2. Thirty-seven (53%) patients had an anosmia which was associated with dysgeusia in 81% of cases. The mean duration of anosmia was 7 days and 51% (36/70) recovery before 28 days of evolution. Only one patient with anosmia had not recovered at the end of the follow-up.
                        • Research Article
                          Open Access

                          Patterns of viral clearance in the natural course of asymptomatic COVID-19: Comparison with symptomatic non-severe COVID-19

                          International Journal of Infectious Diseases
                          Vol. 99p279–285Published online: August 4, 2020
                          • Jae-Sun Uhm
                          • Jin Young Ahn
                          • JongHoon Hyun
                          • Yujin Sohn
                          • Jung Ho Kim
                          • Su Jin Jeong
                          • and others
                          Cited in Scopus: 22
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                            The first cases of coronavirus disease 2019 (COVID-19) were reported in Wuhan, China in December 2019 (Chen et al., 2020; Huang et al., 2020). The pathogen has been identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Lu et al., 2020; Zhu et al., 2020). COVID-19 has rapidly become widespread across the world. In March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. From the end of February through March 2020, Daegu—the fourth largest city in South Korea—was emerging as an epicenter of COVID-19 in South Korea.
                            Patterns of viral clearance in the natural course of asymptomatic COVID-19: Comparison with symptomatic non-severe COVID-19
                          • Research Article
                            Open Access

                            The characteristics and predictive role of lymphocyte subsets in COVID-19 patients

                            International Journal of Infectious Diseases
                            Vol. 99p92–99Published online: August 3, 2020
                            • Wenjing Zhang
                            • Lei Li
                            • Jihai Liu
                            • Li Chen
                            • Fangfang Zhou
                            • Ting Jin
                            • and others
                            Cited in Scopus: 24
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                              The outbreak of coronavirus disease 2019 (COVID-19) in early 2020 has now become an unprecedented global health crisis (Zhu et al., 2020; Li et al., 2020). On March 11, 2020, the World Health Organization announced that COVID-19 had the characteristics of a global pandemic (World Health Organization, 2019a). The pandemic has since accelerated at an exponential rate. Currently, COVID-19 has spread to more than 200 countries and regions around the world. As of 6 June 2020, there were 6 772 520 confirmed cases and 393 843 deaths from COVID-19 (World Health Organization, 2019b; Onder et al., 2020).
                              The characteristics and predictive role of lymphocyte subsets in COVID-19 patients
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