Coronavirus (COVID-19) Collection
Differential clinical characteristics and performance of home antigen tests between parents and children after household transmission of SARS-CoV-2 during the Omicron variant pandemic
The SARS-CoV-2 Omicron variant (B.1.1.529) BA.2 pandemic struck in 2022. Children seemed to have a lower rate of infection than adults at the beginning of the COVID-19 pandemic, but the clinical scenario changed, especially after the Omicron variant outbreak [1]. The transmission of SARS-CoV-2 may vary according to different viral variants, settings, and individuals, and understanding the transmission rate and factors associated with transmission may help further control COVID-19. To this end, the difference in clinical symptoms and overall household transmission rate between children and adults needs further investigation.The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19
SARS-CoV-2, the virus causing Coronavirus disease 2019 (COVID-19), has infected more than 92 million people and lead to the death of more than 1.9 million people worldwide since its outbreak in December 2019 (WHO, 2020). The disease has a wide range of presentations, from asymptomatic infection to fever, cough, shortness of breath and the loss of taste and smell. Symptoms normally appear 2–14 days following exposure to the virus and may develop into mild upper respiratory tract infections or progress to severe pneumonia, which can progress to acute respiratory distress, shock, multiorgan failure and death (Huang et al., 2020; Wang et al., 2020).
