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International Journal of Infectious Diseases
International Society for Infectious Diseases
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  • Research Article
    Open Access

    The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19

    International Journal of Infectious Diseases
    Vol. 105p656–661Published online: February 26, 2021
    • Marwa Ali Almadhi
    • Abdulkarim Abdulrahman
    • Sayed Ali Sharaf
    • Dana AlSaad
    • Nigel J. Stevenson
    • Stephen L. Atkin
    • and others
    Cited in Scopus: 28
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      SARS-CoV-2, the virus causing Coronavirus disease 2019 (COVID-19), has infected more than 92 million people and lead to the death of more than 1.9 million people worldwide since its outbreak in December 2019 (WHO, 2020). The disease has a wide range of presentations, from asymptomatic infection to fever, cough, shortness of breath and the loss of taste and smell. Symptoms normally appear 2–14 days following exposure to the virus and may develop into mild upper respiratory tract infections or progress to severe pneumonia, which can progress to acute respiratory distress, shock, multiorgan failure and death (Huang et al., 2020; Wang et al., 2020).
      The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19
    • Perspective
      Open Access

      Low-dose and oral exposure to SARS-CoV-2 may help us understand and prevent severe COVID-19

      International Journal of Infectious Diseases
      Vol. 103p37–41Published online: November 20, 2020
      • William P. Hausdorff
      • Jorge Flores
      Cited in Scopus: 6
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        Where efficiently applied, a broad range of restrictive non-pharmaceutical interventions (NPI) has succeeded in preempting or mitigating explosive outbreaks of coronavirus disease 2019 (COVID-19) hospitalizations and deaths in many settings. Elsewhere, it has proven difficult to fully implement, maintain, or reimpose these interventions. Much of the public reluctance lies in their huge social and economic consequences, exacerbated by the failure of political leaders to convincingly advocate for these measures.
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