Streptococcus pneumoniae remains the most common cause of community-acquired pneumonia (Van der Poll and Opal, 2009; Johansson et al., 2010). Among pneumonia pathogens, it is the leading cause of hospitalization and death in adults (Roson et al., 2001; Shariatzadeh et al., 2005). Approximately 15–25% of cases of pneumococcal pneumonia are bacteraemic (Said et al., 2013), and bacteraemic pneumococcal community-acquired pneumonia (B-PCAP) has traditionally been considered an invasive form of infection related to higher inflammatory status, worse in-hospital course and shorter long-term survival (Capelastegui et al., 2014; Ishiguro et al., 2016; Ruiz et al., 2019).