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        Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild-to-moderate SARS-CoV-2 in Qatar

          Zaqout et al.
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  • Research Article
    Open Access

    Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild-to-moderate SARS-CoV-2 in Qatar

    International Journal of Infectious Diseases
    Vol. 124p96–103Published online: September 19, 2022
    • Ahmed Zaqout
    • Muna A. Almaslamani
    • Hiam Chemaitelly
    • Samar A. Hashim
    • Ajithkumar Ittaman
    • Abeir Alimam
    • and others
    Cited in Scopus: 4
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      Several monoclonal antibodies against SARS-CoV-2 have been developed for the treatment of COVID-19 (Miguez-Rey et al., 2022). One of these is sotrovimab, which significantly reduced the risk of COVID-19 hospitalization and death due to infection with pre-Omicron SARS-CoV-2 variants in a randomized clinical trial (Gupta et al., 2021). The United States Food and Drug Administration (FDA) issued an emergency authorization to permit the use of sotrovimab for the treatment of mild-to-moderate COVID-19 in patients at high risk of progression to severe COVID-19 (US Food and Drug Administration, 2022).
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