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Coronavirus (COVID-19) Collection
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- ReviewOpen Access
Immunogenicity and efficacy of COVID-19 vaccines in people living with HIV: a systematic review and meta-analysis
International Journal of Infectious DiseasesVol. 124p212–223Published online: October 11, 2022- Juntao Yin
- Yangyang Chen
- Yang Li
- Chaoyang Wang
- Xingwang Zhang
Cited in Scopus: 2The transmission of SARS-CoV-2 has led to the ongoing global COVID-19 pandemic. By August 19, 2022, more than 590 million have had confirmed COVID-19 and more than 6 million have died worldwide (World Health Organization, 2022). The morbidity and mortality from COVID-19 and its complications and large-scale economic disruption have prompted an unprecedented pace in highly efficacious vaccine development (Berlin et al., 2020; Merad et al., 2022). As of August 19, 2022, a total of 12.4 billion vaccine doses have been administered (World Health Organization, 2022), and the most widely used are messenger RNA (mRNA) vaccines, including BNT162b2 (Pfizer-BioNTech, New York, NY, USA-Mainz, Germany) and mRNA-1273 (Moderna, Cambridge, MA, USA) vaccines and viral vector vaccines, such as Ad26.CoV2.S (Johnson & Johnson, New Brunswick, NJ, USA), ChAdOx (AstraZeneca, Cambridge, UK), Sputnik V (Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia), and the traditional inactivated virus alum-adjuvanted candidate vaccine CoronaVac (Sinovac, Beijing, China) (Piccaluga et al.